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The effect of metabolism on the immune system – HealthifyMe

Written by hana

The delicate balance between our metabolism and immune response strongly influences many chronic diseases, including obesity, diabetes, and cardiovascular disease. A safe immune reaction requires energy. How our bodies regulate and manage our metabolism, and our bodies’ ability to defend against pathogens (immune response) are closely related.

The immune system is made up of different cells, each with a specific function to combat threats, protect the body, improve health, and speed up healing. These cells depend on the body’s metabolism to provide the right fuel at the right time in order to function effectively. Therefore, the immune response may be insufficient if the cells do not get enough energy. On the other hand, an overactive immune response can cause immune cells to attack their own healthy tissues.

Immune cells respond differently to different microbes associated with changes in energy metabolism. Furthermore, a healthy diet affects the host’s metabolism, and as a result, a healthy diet affects immune cell responses.

The term metabolism refers to a series of chemical processes in the cells of living organisms to maintain life, including converting food and liquids into energy and building or repairing your body. In addition, metabolic processes allow individuals to maintain their structures, produce offspring, and grow in response to their environment. Metabolism includes all chemical processes, from digestion to the movement of chemicals from one cell to another.

Metabolism and the human body

Human metabolism is divided into two distinct components, catabolism, and metabolism. It is precisely what the body regulates to maintain its balance despite its complexity. Catabolism refers to the breakdown of nutrients into simpler forms, such as carbohydrates, proteins, and dietary fats, so that your body can use them as fuel and the building blocks for development and repair. The part of metabolism known as metabolism is where the body is built or repaired. The energy needed for metabolism ultimately comes from food. The extra nutrients you consume over the body’s needs for daily anabolic process are stored as fat.

When your metabolic systems are working properly, there is a low chance of developing disorders that may harm your overall health. On the other hand, when you’re not in good metabolic health, your cells, specifically the energy-producing units within cells called mitochondria, can’t produce the energy they need to function properly. Thus dysfunction and disease can occur.

The immune system is one of the body’s most important defenders, acting as a bodyguard to keep infection and disease at bay. The need to better understand the intricacies of this system is growing as immunotherapies continue to be developed to treat metabolic diseases. The complex network of metabolism and the immune system is described in this article from a nutritional point of view.

HealthifyMe Note

The immune system produces white blood cells and other chemicals and proteins that target and remove unwanted pathogens or microbes. Your immune system needs an efficient metabolism to do the hard work of protecting your body.

HealthifyPRO 2.0 puts you in control of your health and makes it easy to fully and routinely understand your health parameters. It is necessary to keep your metabolism healthy. A smart scale, metabolic panel, CGM and other trackers help you maintain your metabolic health. The metabolic panel analyzes your blood according to 80 criteria. It also has a wearable device called a BIOS that notifies you of the effect of food on your blood sugar levels. In addition, it helps you keep track of your glucose levels. As a result, the coach helps you design a customized diet plan for better metabolism and metabolic health.

Every cell in the body undergoes metabolism, including immune cells. That’s because the process of immune cell production is metabolic activity. The effectiveness and reliability of metabolic processes determine how their products and by-products appear. As a result, it is necessary to control the body’s immunity and its effectiveness. There is a close relationship between the immune system and metabolism. Two of the cell’s most essential tasks are to obtain enough nutrients and energy to sustain life and protect itself from potentially dangerous microorganisms.

In this context, it is not surprising that the immune system is closely linked to metabolic activity. According to a study, the energy needed for the immune response is obtained, including the production and preparation of white blood cells to fight infections and diseases. One of the most powerful bodily defense mechanisms is the immune system, which is equipped with a large number of defense cells that can eliminate the infection with which it comes in contact.

The body also has several safe mechanisms in place to prevent the immune system from attacking itself. However, sometimes these means of protection fail, and we feel an unwarranted inflammatory reaction. Monitoring the influx of immune cells, such as T cells and B cells, and migration to organs and tissues is the most direct way to measure this response.

The immune system is commonly called a “quiet state” in healthy individuals; He is looking for infection but is not actively involved in combat mode. Instead, immune cells speed up their metabolism and take in more nutrients when an attack is imminent to generate proteins needed for defense, such as cytokines and antibodies.

The metabolic pathways of the immune system are a check and balance system used to control the response. The immune system can fool itself into thinking it is starving by suppressing the immune response and shutting down the metabolism.

Metabolism forms the basis for the production of high-quality immune cells. Any change in the process can lead to deficits and malfunctions of immune cells. For example, manufacturing defective products requires only poor performance and operational adjustments. Correction or intervention aimed at appropriate production gives only the best functional output. The same is true for immune cells. An altered metabolism that creates malfunctioning cells can only lead to disruption. Interventions to correct or attenuate metabolic processes can produce almost desirable results.

There is no “magic pill” or supplement that can significantly boost your immune system. On the other hand, research findings support the idea that lifestyle changes are the best way to maintain your immune system’s ability to fight infection and boost immune strength. An essential part of your metabolism is effectively using your fuel reserves and converting them into energy to help your immune system.

Here are some factors that can enhance metabolic flexibility and are also essential for a well-built immune system:

Good sleep is essential

Your immune system needs rest to be strong and alert. The immune system and sleep are interrelated and affect each other. Studies show a direct link between sleep deprivation and an increased risk of disease. Because of decreased synthesis of cytokines, which are molecules that make up the immune response, lack of sleep weakens your immune system.

Additionally, a study found an important relationship between the immune system and circadian rhythm, or “biological clocks,” in humans. These clocks update based on your actions, including how much sunlight you receive, when you eat, and how much you sleep.

The immune system and the patterns of physiological cycles that occur daily in every cell of the body are regulated by biological clocks, which also control metabolism. Recent research suggests that interference with these clocks due to lack of sleep may negatively affect the defense processes of immune cells.

Make sure to establish a regular sleep pattern with at least 6 to 7 hours of quality sleep to prevent this and keep your immune system healthy.

Stress damages the immune system

Mind and body are intricately linked. Also, stress comes in different forms. However, there is a difference between acute and chronic stress. In either case, the body’s physiological response causes the release of neurotransmitters and hormones that prime it for a “fight or flight” response, raising blood sugar, blood pressure, and heart rate. Even while the “stress reaction” is a survival mechanism in nature, chronic exposure to it weakens your immune system.

The “stress hormone”, cortisol, which also affects the functioning of one of the vital components of your immune system, T cells, is the cause of this (lymphocytes). These cells identify the affected cells and send a signal or even counteract them. But according to a study, the immune response is affected when these cells are exposed to elevated levels of cortisol over a long period.

Micronutrients help you stay alert

Calories, carbs, fat, and protein aren’t the only factors to consider. Your immune system must get enough vitamins, minerals, and other “micronutrients” to function efficiently. With specific minerals like iron, zinc, copper, and selenium, vitamins A, B6, B12, C, D, E, and folic acid help your immune system’s defense mechanisms. Vitamin B12 is essential for everyone. Besides vitamin B12, eating a mix of legumes and a bunch of colorful vegetables will give you all the micronutrients you need on a daily basis.

It’s easy to make sure you’re consuming all the vitamins and minerals your body needs. Natural substances found in fruits and vegetables, such as phytochemicals, are also linked to their forms. According to a study, these compounds will have a synergistic effect in strengthening your immune system.

Start by checking the colors in your refrigerator. If all you have are carbohydrates and fats, you should add yellow, red, green and purple vegetables. Make your plate as colorful as possible to properly support your immune system. It will give you the right amount of fibre. Please also include proteins in your meals to improve your metabolic health.

Avoid smoking and alcohol consumption

Smoking and excessive alcohol intake are known to suppress immunity. Therefore, it is advisable to completely avoid smoking, or reduce it slowly. Also, reducing or even stopping alcohol intake can have a better immune effect.

Several studies have proven that smoking and alcohol consumption impair the immune response. It reduces IgG levels regardless of diagnosis or treatment. Furthermore, alcohol disrupts immune pathways in complex ways. These disorders can impair the body’s ability to fight infection and cause organ damage.

stay healthy

Reducing microbial invasion is as vital as strengthening or improving the immune system. It is a good practice to wash your hands for at least 20 seconds. Others include keeping the house clean and changing the clothes that are worn outside. Similar habits, if practiced, can eliminate avoidable bacteria.

HealthifyMe Note

Robust interior ensures external strength. The key to having a strong immune system is to provide your body with the nutrients it needs to function at its best. Your metabolic flexibility determines your body’s ability to convert food into energy and produce new immune cells needed to fight off viruses and attacks.


Metabolism and immunity are closely linked, and they influence each other at every stage. Almost every aspect of immune health and disease is affected by metabolic factors. The effect ranges from cellular reproduction to immune cell maturation and training. Almost all immune diseases such as deficiency syndromes, type 1 diabetes, systemic lupus erythematosus, rheumatoid arthritis, asthma, allergic rhinitis, eczema, and even cancers are affected by metabolism. Maintaining a healthy metabolism can promote better immunity, too. Proper lifestyle habits, nutritional advice, thought processes, and other limitations can all be beneficial for disease-free health!

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